how to switch antidepressants

June 2006

We're getting questions about how to switch antidepressants.

A recent NIH study shows that switching antidepressants can help. But it can be tricky to do.

Direct switch. Some patients can switch directly from one SSRI to another SSRI, Effexor, or Cymbalta. For example, you can often switch a patient on Zoloft to another SSRI the next day.

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